RNA platform

Your mRNA Medicine.
Engineered for Success.

Design, synthesize, and fine-tune your mRNA therapeutics
for unparalleled efficacy and safety.
We leverage pioneering machine learning technology
to boost translation and achieve unmatched tissue specificity
by precision-engineering non-coding regions
uniquely tailored to your mRNA.

UTRs design

DNA Template

In Vitro Transcription

Quality Control

The RNA pipeline to unlock your next breakthrough

UTR design

Design for efficacy and safety

Boost expression and control tissue specificity by leveraging non-coding regions to modulate gene expression, translation efficiency, and mRNA stability.

Leveraging our platform in precision DNA synthesis and machine learning, our team of experts craft UTRs optimized for your desired outcomes and cell type. Our UTR design has been shown to improve performance in RNA therapeutic safety and efficacy for leading research groups.

up to 5X protein expression

up to 4.6X tissue specificity

up to 2x longer expression

Design your RNA

Instant quote

Design your RNA

Our combinatorial design approach for UTR optimisation ensures the most effective UTR sequence for your application

DNA template synthesis

Design without compromising

Design your RNA therapeutics for what you actually need without limits.

Thanks to our unparalleled ability to synthesize any template, we routinely tackle long & complex coding sequences and UTRs that could limit the design space available for RNA therapeutic development.

High frequency repeats

GC content 15 - 85%

Homopolymeric stretches < 150 nt

Build your template

Instant quote

Build your template

We're leaders in complex DNA synthesis so that you should never compromise again on your design.

In Vitro Transcription

The fastest path from design to test

We leverage our ML platform to optimize the in vitro transcription of your mRNA to maximize yield and minimize dsRNA and truncated products, ensuring you can confidently move from design to testing as quickly as possible.

We understand the pivotal role of capping in enhancing RNA stability, translational efficiency, and biological activity. Whether you require traditional capping or superior performance of CleanCap's reduced immunogenicity, our customizable solutions cater to your needs.

Transcripts up to 10 kilobases

50ug to 10mg

Different capping option and N1-methylpseudouridine available

Precise length Poly A tails with defined lengths from 40 to 160 nt

Synthesize your RNA

Instant quote

Synthesize your RNA

Our precise length PolyA tails are synthesised to ensure full control over transcript expression

Quality Control

Reproducible, reliable results

Ensuring pristine RNA quality is paramount in the pursuit of reliable and reproducible results, and our stringent quality control standards guarantee excellence at every step. Employing industry-leading benchmarks, we meticulously assess RNA integrity and purity to meet the highest scientific standards.

A260/A280 ratio within 1.8–2.2,

A260/A230 threshold exceeding 1.7

RNA Integrity Number (RIN) threshold above 8

(LAL) chromogenic assay certifies that endotoxin levels remain below 0.5 EU/mL

Our rigorous quality control standards provide the most reliable RNA for research

Your mRNA Medicine.
Engineered for Success.

The RNA pipeline to unlock your next breakthrough

UTR design